Graduate Students
Bjorn-Erik Wulff
I am creating a way to solve high-resolution protein structures within the living cell. I do this by first chemically cross-linking adjacent protein residues inside the cell and then detecting the cross-links by mass spectrometry. This gives residue-residue distance constraints from which the structure can be solved computationally.
Jenna Caldwell
Conformational change is integral to the function of many proteins, but it is difficult to observe using current methods, particularly in complex, physiologically relevant environments. I am developing a solvent exposure-based method that will allow us to observe these conformational changes.
Dan Riordan
My research focuses on the discovery and characterization of human cell types and tissue features using multiplexed gene expression profiling. To this end, I am developing new technologies for spatial transcriptome mapping with single-cell resolution. I am also engineering novel luminescent probes for enhanced detection of specific biomolecules.
Research Associates
Undergraduate Students
Jason Tung
My research focuses on developing efficient multiplexed methods for accurate in situ mapping of biological structures. In order to achieve this goal, I am developing compounds to link antibodies with oligonucleotide-barcoded probes and optimizing whole mount electrophoresis-mediated antibody delivery into tissue samples.
Rotating Students
Peter Chou
Summer Interns
Dan Ma
2016 Intern